Seipin deficiency in mouse is related with tau phosphorylation through PPARG reduction in neurons

March 30, 2019 at 10:31 pm

Seipin deletion in mice enhances phosphorylation and aggregation of tau protein through reduced neuronal PPARG and insulin resistance.

Chang H et al.
Neurobiol Dis. 2019.
doi: 10.1016/j.nbd.2019.03.023.

https://www.ncbi.nlm.nih.gov/m/pubmed/30910747/